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This page provides information and toolkits to support healthcare professionals who are requesting germline genetic tests for inherited ovarian cancer. This page provides information and toolkits to support healthcare professionals who are requesting germline genetic tests for inherited ovarian cancer. The toolkits provide a step by step guide for selecting and arranging these tests, including key forms for consent and arranging samples. Note: these toolkits are for germline tests. For somatic tests see SWGLH Requesting a Genomic Test for Solid Tumours

Step by step instructions

Test code

R207 Inherited Ovarian Cancer

Visit the NHS Genomic Test Directory 

Eligibility

Eligibility criteria for genomic tests can be found in the National Genomic Test Directory.

This lists the clinical specialties that would be expected to request for a given clinical indication and sets out which patients should be considered for testing.

Consent

Germline genetic tests have implications for future and family health. Patients should be informed of the implications and appropriately consented, using a tool such as the Mainstreaming Consent Form to document in the patient record. The below Patient information leaflet can be used with or without local trust logo to support patient information provision.

Mainstreaming Consent form for Inherited Cancer V1.3

R207 Patient Information Leaflet V1 TRUST LOGO

R207 Patient Information Leaflet V1 GLH LOGO

 

Test order form

All samples for genomic testing should be accompanied by a fully completed request form.

The request form should include as much clinical information about the patient or family member, family relationships and the requested test code (R number). All request forms must indicate either a specific disorder/gene(s) to be investigated or, a request to extract and store DNA.

This form should be used for the majority of test requests.

Please do not download and store this on your desktop or system. The form is regularly updated. Our recommendation is to save or bookmark a link to our website to ensure you are working with the most up-do-date version.

Download the latest version here: GMS Test Order Form v2.3

Samples and transport

Before sending samples for genomic testing, please ensure you follow the correct preparation and transport guidelines. This includes information on sample types, volumes, handling, labelling, and packaging standards.

For a full list of sample requirements and transport guidance, please visit the samples and transport page of the website. 

Results and turnaround times

Turnaround times (TATs) for genomic tests are continually refined through ongoing reviews of testing standards.

Results will be returned to the email account or clinician listed on the request form.

Visit the results and turnaround page for more information.

Important contact information

Once results are received, please see your local mainstreaming guidance for information on management and Clinical Genetics involvement. If you need advice, contact your local Clinical Genetics service.

Devon and Cornwall region: rduh.pcgreferrals@nhs.net (or via the Epic system if you are based at the Royal Devon University Healthcare NHS  Foundation Trust)

Bristol region: UHBWClinicalGenetics@uhbw.nhs.uk